Found 35 matching trials
TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors PHASE2 The purpose of this study is to find out if removing a specific type of whi...
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Memorial SloanKettering Cancer Center
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Phase III Trial of Sirolimus in IBM PHASE3 The hypothesis is that Sirolimus, (Rapamycin (R)) which is currently used i...
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Active Not Recruiting
Location
University of Kansas Medical Center
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Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML PHASE2 RATIONALE: Giving low doses of chemotherapy, such as fludarabine, and total...
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OHSU Knight Cancer Institute
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PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer PHASE1 This study will evaluate the safety of PD-1 knockout engineered T cells in ...
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West China Hospital, Sichuan University
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CTLA-4 and PD-1 Antibodies Expressing MUC1-CAR-T Cells for MUC1 Positive Advanced Solid Tumor PHASE1 This is a single-arm, open-label, one center clinical study, to determine t...
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Ningbo No.5 Hospital (Ningbo Cancer Hospital)
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Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases PHASE2 This phase II trial investigates how well a naive T cell depleted graft wor...
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Seattle Children's Hospital
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A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1 Background:
GM1 gangliosidosis is a disorder that destroys nerve cells. It...
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National Institutes of Health Clinical Center
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Safety and Efficacy of BiTE in Desensitization Therapy for Highly Sensitized Kidney Transplant Candidates With cPRA ≥ 90% PHASE4 This study is a prospective, open-label, two-arm exploratory clinical trial...
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Multiple Locations
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QUILT-3.034: Non-Myeloablative TCRa/b Deplete Haplo HSCT With Post ALT-803 for AML PHASE2 This is a phase II multi-institutional therapeutic study of a non-myeloabla...
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Masonic Cancer Center
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Evaluating the Use of RFT5-dgA to Deplete Alloreactive Cells Prior to Haploidentical Stem Cell Transplantation PHASE1 This study is designed to determine the number of donor lymphocytes that ca...
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Methodist Hospital
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